Failed to access IIS metabase

We followed below steps to resolve the issue -

1. Unregistered all the versions of ASP.NET with command "C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\aspnet_regiis –ua".

2. Deleted the ASPNET account from "Local Users and Group – Users".

3. Then registered ASP.NET 2.0 with IIS using "C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\aspnet_regiis –i".

4. Gave permissions to the ASPNET account using "C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\aspnet_regiis –ga machinename\ASPNET".

5. Reset the IIS and that resolved the issue for ASP.NET 2.0.

6. We registered ASP.NET 1.1 with IIS as well using command "C:\WINDOWS\Microsoft.NET\Framework\v1.1.4322\aspnet_regiis –i".

7. Reset the IIS.

source: http://forums.asp.net/post/4547026.aspx